Position-independent, high-level expression of the human beta-globin gene in transgenic mice.

Position-independent, high-level expression of the human beta-globin gene in transgenic mice.

We have constructed a "minilocus" that contains the 5' and 3' flanking regions of the human beta-globin locus and the beta-globin gene. These regions are characterized by erythroid-specific DNAase I-superhypersensitive sites and are normally located approximately 50 kb 5' an...

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Bibliographic Details
Main Authors:	Grosveld, F, van Assendelft, G, Greaves, D, Kollias, G
Format:	Journal article
Language:	English
Published:	1987

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