A modular, enantioselective synthesis of resolvins D3, E1, and hybrids
Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama-Denmark coupling of five- and six-membered cyclic alkenylsiloxanes to connect three resolvin fragments, and contr...
Main Authors: | Urbitsch, F, Elbert, BL, Llaveria, J, Streatfeild, PE, Anderson, EA |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2020
|
Similar Items
-
Synthesis and biology of resolvins D3, E1 and hybrids and synthesis of bridge-substituted bicyclo[1.1.1]pentanes
by: Urbitsch, F
Published: (2019) -
Synthesis of cyclic alkenyl dimethylsiloxanes from alkynyl benzyldimethylsilanes and application in polyene synthesis
by: Gudmundsson, HG, et al.
Published: (2019) -
Resolvin D1 and Resolvin E1 Promote the Resolution of Allergic Airway Inflammation Via Shared and Distinct Molecular Counter-Regulatory Pathways
by: Bruce D Levy
Published: (2012-12-01) -
Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
by: Lucy V. Norling, et al.
Published: (2023-02-01) -
Pleiotropic antifibrotic actions of aspirin-triggered resolvin D1 in the lungs
by: Rafael F. Guilherme, et al.
Published: (2023-03-01)