A modular, enantioselective synthesis of resolvins D3, E1, and hybrids

Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama-Denmark coupling of five- and six-membered cyclic alkenylsiloxanes to connect three resolvin fragments, and contr...

Повний опис

Бібліографічні деталі
Автори: Urbitsch, F, Elbert, BL, Llaveria, J, Streatfeild, PE, Anderson, EA
Формат: Journal article
Мова:English
Опубліковано: American Chemical Society 2020