Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis.

Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis.

Melioidosis (infection caused by Burkholderia pseudomallei) requires a prolonged course of oral antibiotics following initial intravenous therapy to reduce the risk of relapse after cessation of treatment. The current recommendation is a four-drug regimen (trimethoprim [TMP], sulfamethoxazole [SMX],...

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Bibliographic Details
Main Authors: Chaowagul, W, Chierakul, W, Simpson, A, Short, J, Stepniewska, K, Maharjan, B, Rajchanuvong, A, Busarawong, D, Limmathurotsakul, D, Cheng, A, Wuthiekanun, V, Newton, P, White, N, Day, N, Peacock, S
Format: Journal article
Language:English
Published: 2005

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