FcRγ controls the fas-dependent regulatory function of lymphoproliferative double negative T cells

FcRγ controls the fas-dependent regulatory function of lymphoproliferative double negative T cells

Patients with autoimmune lymphoproliferative syndrome (ALPS) and lymphoproliferation (LPR) mice are deficient in Fas, and accumulate large numbers of αβ-TCR+, CD4−, CD8− double negative (DN) T cells. The function of these DN T cells remains largely unknown. The common γ subunit of the activating Fc...

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Autors principals:	Juvet, S, Thomson, C, Kim, E, Han, M, Zhang, L
Format:	Journal article
Idioma:	English
Publicat:	Public Library of Science 2013

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