Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development

Background:Diagnostic tests' impact on patient outcomes and health processes is potentially large, and proper evaluations before widespread adoption are warranted. Such evaluations are challenged by the fact that tests can have multiple purposes, in different clinical pathways, with different r...

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Main Authors: Van Den Bruel, A, Hayward, G
Format: Journal article
Language:English
Published: BioMed Central 2018
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author Van Den Bruel, A
Hayward, G
author_facet Van Den Bruel, A
Hayward, G
author_sort Van Den Bruel, A
collection OXFORD
description Background:Diagnostic tests' impact on patient outcomes and health processes is potentially large, and proper evaluations before widespread adoption are warranted. Such evaluations are challenged by the fact that tests can have multiple purposes, in different clinical pathways, with different roles. Body:The National Institute for Health Research (NIHR) established four Diagnostic Evidence Cooperatives (DEC) in 2013, across England. The aim of these DECs was to facilitate the development and evaluation of clinically relevant in vitro diagnostics, by offering methodological expertise and access to real-life settings for evaluations in patients. In this commentary, we discuss our experience over the past 4 years. Conclusion:The interaction of industry, researchers, and clinicians has proven to be very worthwhile.
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spelling oxford-uuid:2e3abdac-aa32-4efd-a398-cc72ccfbdd322022-03-26T12:47:42ZDiagnostic evidence cooperatives: bridging the valley of death in diagnostics developmentJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2e3abdac-aa32-4efd-a398-cc72ccfbdd32EnglishSymplectic Elements at OxfordBioMed Central2018Van Den Bruel, AHayward, GBackground:Diagnostic tests' impact on patient outcomes and health processes is potentially large, and proper evaluations before widespread adoption are warranted. Such evaluations are challenged by the fact that tests can have multiple purposes, in different clinical pathways, with different roles. Body:The National Institute for Health Research (NIHR) established four Diagnostic Evidence Cooperatives (DEC) in 2013, across England. The aim of these DECs was to facilitate the development and evaluation of clinically relevant in vitro diagnostics, by offering methodological expertise and access to real-life settings for evaluations in patients. In this commentary, we discuss our experience over the past 4 years. Conclusion:The interaction of industry, researchers, and clinicians has proven to be very worthwhile.
spellingShingle Van Den Bruel, A
Hayward, G
Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title_full Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title_fullStr Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title_full_unstemmed Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title_short Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development
title_sort diagnostic evidence cooperatives bridging the valley of death in diagnostics development
work_keys_str_mv AT vandenbruela diagnosticevidencecooperativesbridgingthevalleyofdeathindiagnosticsdevelopment
AT haywardg diagnosticevidencecooperativesbridgingthevalleyofdeathindiagnosticsdevelopment