Antenatal magnesium individual participant data international collaboration: Assessing the benefits for babies using the best level of evidence (AMICABLE)

Background: The primary aim of this study is to assess, using individual participant data (IPD) meta-analysis, the effects of administration of antenatal magnesium sulphate given to women at risk of preterm birth on important clinical outcomes for their child such as death and neurosensory disabilit...

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Bibliographic Details
Main Authors: Crowther, C, Middleton, P, Askie, L, Doyle, L, Bubner, T, Voysey, M
Format: Journal article
Language:English
Published: 2012
Description
Summary:Background: The primary aim of this study is to assess, using individual participant data (IPD) meta-analysis, the effects of administration of antenatal magnesium sulphate given to women at risk of preterm birth on important clinical outcomes for their child such as death and neurosensory disability. The secondary aim is to determine whether treatment effects differ depending on important pre-specified participant and treatment characteristics, such as reasons at risk of preterm birth, gestational age, or type, dose and mode of administration of magnesium sulphate.Methods: Discussion: Results are expected to be publicly available in 2012. © 2012 The AMICABLE Group; licensee BioMed Central Ltd.