Species-specific differences in the expression of the HNF1A, HNF1B and HNF4A genes.

BACKGROUND: The HNF1A, HNF1B and HNF4A genes are part of an autoregulatory network in mammalian pancreas, liver, kidney and gut. The layout of this network appears to be similar in rodents and humans, but inactivation of HNF1A, HNF1B or HNF4A genes in animal models cause divergent phenotypes to tho...

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Main Authors: Harries, L, Brown, J, Gloyn, A
格式: Journal article
语言:English
出版: Public Library of Science 2009