Synthesis and use of cell-permeant cyclic ADP-ribose.

Synthesis and use of cell-permeant cyclic ADP-ribose.

Cyclic ADP-ribose (cADPR) is a second messenger that acts on ryanodine receptors to mobilize Ca(2+). cADPR has a net negative charge at physiological pH making it not passively membrane permeant thereby requiring it to be injected, electroporated or loaded via liposomes. Such membrane impermeance of...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Rosen, D, Bloor-Young, D, Squires, J, Parkesh, R, Waters, G, Vasudevan, SR, Lewis, A, Churchill, G
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2012

Παρόμοια τεκμήρια

Cyclic ADP ribose as a calcium-mobilizing messenger.
ανά: Galione, A, κ.ά.
Έκδοση: (2000)

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death
ανά: Zhi Ying Zhao, κ.ά.
Έκδοση: (2019-05-01)

Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.
ανά: Parkesh, R, κ.ά.
Έκδοση: (2008)

Adp-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor. a primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction.
ανά: Wilson, H, κ.ά.
Έκδοση: (2001)

Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose.
ανά: Boittin, F, κ.ά.
Έκδοση: (2003)

Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.
ανά: Alicia Cabezas, κ.ά.
Έκδοση: (2015-01-01)

Pharmacological characterization of the putative cADP-ribose receptor.
ανά: Thomas, J, κ.ά.
Έκδοση: (2001)

Actions of a membrane permeant analogue of NAADP on contractions and calcium sparks in cardiac ventricular myocytes.
ανά: Rakovic, S, κ.ά.
Έκδοση: (2007)

Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose.
ανά: Shuto, S, κ.ά.
Έκδοση: (2003)

Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose.
ανά: Summerhill, R, κ.ά.
Έκδοση: (1993)

Modulation of store-operated Ca2+ entry by cyclic-ADP-ribose
ανά: Thompson M., κ.ά.
Έκδοση: (2006-01-01)

Actions of cADP-ribose phosphate on contraction in guinea-pig isolated ventricular myocytes
ανά: Macgregor, A, κ.ά.
Έκδοση: (2003)

Biphasic actions of cADP-ribose phosphate on contraction in guinea-pig isolated ventricular myocytes
ανά: Macgregor, A, κ.ά.
Έκδοση: (2002)

Methods for Purification of Proteins Associated with Cellular Poly(ADP-Ribose) and PARP-Specific Poly(ADP-Ribose)
ανά: Rood, Jennifer E., κ.ά.
Έκδοση: (2014)

In Vivo Level of Poly(ADP-ribose)
ανά: Masanao Miwa, κ.ά.
Έκδοση: (2018-05-01)

Changes in NAD/ADP-ribose metabolism in rectal cancer
ανά: L. Yalcintepe, κ.ά.
Έκδοση: (2005-03-01)

Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose (vol 278, pg 9602, 2003)
ανά: Boittin, F, κ.ά.
Έκδοση: (2006)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
ανά: Mathilde Malgras, κ.ά.
Έκδοση: (2021-03-01)

ARH Family of ADP-Ribose-Acceptor Hydrolases
ανά: Hiroko Ishiwata-Endo, κ.ά.
Έκδοση: (2022-11-01)

Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.
ανά: Dowden, J, κ.ά.
Έκδοση: (2006)

Poly ADP-ribose polymerase-1: an international molecule of mystery.
ανά: Woodhouse, B, κ.ά.
Έκδοση: (2008)

Ca2+ release induced by cyclic ADP ribose in mice lacking type 3 ryanodine receptor.
ανά: Fulceri, R, κ.ά.
Έκδοση: (2001)

Inhibition of CD38/Cyclic ADP-ribose Pathway Protects Rats against Ropivacaine-induced Convulsion
ανά: Yu Zou, κ.ά.
Έκδοση: (2017-01-01)

Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
ανά: Ralf Fliegert, κ.ά.
Έκδοση: (2020-08-01)

Toward the synthesis of caged cell membrane permeant phosphatidylinositol polyphosphates.
ανά: Johns, M, κ.ά.
Έκδοση: (2004)

Neuronal accumulation of poly(ADP-ribose) after brain ischaemia.
ανά: Love, S, κ.ά.
Έκδοση: (1999)

Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase.
ανά: Zhizhi Wang, κ.ά.
Έκδοση: (2014-01-01)

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
ανά: Slade, D, κ.ά.
Έκδοση: (2011)

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.
ανά: Gottipati, P, κ.ά.
Έκδοση: (2010)

Poly (ADP-Ribose) Polymerase Cleavage Monitored In Situ in Apoptotic Cells
ανά: Martha A. O'Brien, κ.ά.
Έκδοση: (2001-04-01)

Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.
ανά: Dunstan, MS, κ.ά.
Έκδοση: (2012)

Cooperative nucleic acid binding by Poly ADP-ribose polymerase 1
ανά: Manana Melikishvili, κ.ά.
Έκδοση: (2024-03-01)

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
ανά: Daniel Harrision, κ.ά.
Έκδοση: (2020-08-01)

Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.
ανά: Markus Dahl, κ.ά.
Έκδοση: (2014-01-01)

Role of poly(ADP-ribose) polymerase-1 in regulating human islet cell differentiation
ανά: Nidheesh Dadheech, κ.ά.
Έκδοση: (2022-12-01)

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.
ανά: Chen, D, κ.ά.
Έκδοση: (2011)

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.
ανά: Chen, D, κ.ά.
Έκδοση: (2011)

Erratum: Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose (Journal of Biological Chemistry (2003) 278, (9602-9608))
ανά: Boittin, F, κ.ά.
Έκδοση: (2006)

Family-wide analysis of poly(ADP-ribose) polymerase activity
ανά: Vyas, Sejal, κ.ά.
Έκδοση: (2015)

The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis
ανά: Samuel García, κ.ά.
Έκδοση: (2015-01-01)