Synthesis and use of cell-permeant cyclic ADP-ribose.

Synthesis and use of cell-permeant cyclic ADP-ribose.

Cyclic ADP-ribose (cADPR) is a second messenger that acts on ryanodine receptors to mobilize Ca(2+). cADPR has a net negative charge at physiological pH making it not passively membrane permeant thereby requiring it to be injected, electroporated or loaded via liposomes. Such membrane impermeance of...

Descripció completa

Dades bibliogràfiques
Autors principals:	Rosen, D, Bloor-Young, D, Squires, J, Parkesh, R, Waters, G, Vasudevan, SR, Lewis, A, Churchill, G
Format:	Journal article
Idioma:	English
Publicat:	2012

Ítems similars

Cyclic ADP ribose as a calcium-mobilizing messenger.
per: Galione, A, et al.
Publicat: (2000)

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death
per: Zhi Ying Zhao, et al.
Publicat: (2019-05-01)

Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.
per: Parkesh, R, et al.
Publicat: (2008)

Adp-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor. a primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction.
per: Wilson, H, et al.
Publicat: (2001)

Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose.
per: Boittin, F, et al.
Publicat: (2003)

Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase.
per: Alicia Cabezas, et al.
Publicat: (2015-01-01)

Pharmacological characterization of the putative cADP-ribose receptor.
per: Thomas, J, et al.
Publicat: (2001)

Actions of a membrane permeant analogue of NAADP on contractions and calcium sparks in cardiac ventricular myocytes.
per: Rakovic, S, et al.
Publicat: (2007)

Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose.
per: Shuto, S, et al.
Publicat: (2003)

Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose.
per: Summerhill, R, et al.
Publicat: (1993)

Modulation of store-operated Ca2+ entry by cyclic-ADP-ribose
per: Thompson M., et al.
Publicat: (2006-01-01)

Actions of cADP-ribose phosphate on contraction in guinea-pig isolated ventricular myocytes
per: Macgregor, A, et al.
Publicat: (2003)

Biphasic actions of cADP-ribose phosphate on contraction in guinea-pig isolated ventricular myocytes
per: Macgregor, A, et al.
Publicat: (2002)

Methods for Purification of Proteins Associated with Cellular Poly(ADP-Ribose) and PARP-Specific Poly(ADP-Ribose)
per: Rood, Jennifer E., et al.
Publicat: (2014)

In Vivo Level of Poly(ADP-ribose)
per: Masanao Miwa, et al.
Publicat: (2018-05-01)

Changes in NAD/ADP-ribose metabolism in rectal cancer
per: L. Yalcintepe, et al.
Publicat: (2005-03-01)

Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose (vol 278, pg 9602, 2003)
per: Boittin, F, et al.
Publicat: (2006)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
per: Mathilde Malgras, et al.
Publicat: (2021-03-01)

ARH Family of ADP-Ribose-Acceptor Hydrolases
per: Hiroko Ishiwata-Endo, et al.
Publicat: (2022-11-01)

Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.
per: Dowden, J, et al.
Publicat: (2006)

Poly ADP-ribose polymerase-1: an international molecule of mystery.
per: Woodhouse, B, et al.
Publicat: (2008)

Ca2+ release induced by cyclic ADP ribose in mice lacking type 3 ryanodine receptor.
per: Fulceri, R, et al.
Publicat: (2001)

Inhibition of CD38/Cyclic ADP-ribose Pathway Protects Rats against Ropivacaine-induced Convulsion
per: Yu Zou, et al.
Publicat: (2017-01-01)

Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
per: Ralf Fliegert, et al.
Publicat: (2020-08-01)

Toward the synthesis of caged cell membrane permeant phosphatidylinositol polyphosphates.
per: Johns, M, et al.
Publicat: (2004)

Neuronal accumulation of poly(ADP-ribose) after brain ischaemia.
per: Love, S, et al.
Publicat: (1999)

Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase.
per: Zhizhi Wang, et al.
Publicat: (2014-01-01)

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
per: Slade, D, et al.
Publicat: (2011)

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.
per: Gottipati, P, et al.
Publicat: (2010)

Poly (ADP-Ribose) Polymerase Cleavage Monitored In Situ in Apoptotic Cells
per: Martha A. O'Brien, et al.
Publicat: (2001-04-01)

Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.
per: Dunstan, MS, et al.
Publicat: (2012)

Cooperative nucleic acid binding by Poly ADP-ribose polymerase 1
per: Manana Melikishvili, et al.
Publicat: (2024-03-01)

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
per: Daniel Harrision, et al.
Publicat: (2020-08-01)

Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.
per: Markus Dahl, et al.
Publicat: (2014-01-01)

Role of poly(ADP-ribose) polymerase-1 in regulating human islet cell differentiation
per: Nidheesh Dadheech, et al.
Publicat: (2022-12-01)

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.
per: Chen, D, et al.
Publicat: (2011)

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.
per: Chen, D, et al.
Publicat: (2011)

Erratum: Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose (Journal of Biological Chemistry (2003) 278, (9602-9608))
per: Boittin, F, et al.
Publicat: (2006)

Family-wide analysis of poly(ADP-ribose) polymerase activity
per: Vyas, Sejal, et al.
Publicat: (2015)

The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis
per: Samuel García, et al.
Publicat: (2015-01-01)