Synthesis and use of cell-permeant cyclic ADP-ribose.

Synthesis and use of cell-permeant cyclic ADP-ribose.

Cyclic ADP-ribose (cADPR) is a second messenger that acts on ryanodine receptors to mobilize Ca(2+). cADPR has a net negative charge at physiological pH making it not passively membrane permeant thereby requiring it to be injected, electroporated or loaded via liposomes. Such membrane impermeance of...

Bibliografske podrobnosti
Main Authors:	Rosen, D, Bloor-Young, D, Squires, J, Parkesh, R, Waters, G, Vasudevan, SR, Lewis, A, Churchill, G
Format:	Journal article
Jezik:	English
Izdano:	2012

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