Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.

Adaptive responses to hypoxia occur in many biological systems. A well-characterized example is the hypoxic induction of the synthesis of erythropoietin, a hormone which regulates erythropoiesis and hence blood oxygen content. The restricted expression of the erythropoietin gene in subsets of cells...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Maxwell, P, Pugh, C, Ratcliffe, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1993