Epitopes of the CD4 antigen and HIV infection.

Epitopes of the CD4 antigen and HIV infection.

The CD4 (or T4) surface antigen of human T lymphocytes is an important part of the receptor for the human immunodeficiency virus (HIV). After binding to the receptor, the HIV may enter the T cell and induce the formation of syncytia. In an attempt to identify the receptor site more closely, monoclon...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Sattentau, Q, Dalgleish, A, Weiss, R, Beverley, P
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	1986

Antzeko izenburuak

The role of the CD4 antigen in HIV infection and immune pathogenesis.
nork: Sattentau, Q
Argitaratua: (1988)

The CD4 antigen: physiological ligand and HIV receptor.
nork: Sattentau, Q, et al.
Argitaratua: (1988)

HIV infection of primate lymphocytes and conservation of the CD4 receptor.
nork: McClure, M, et al.
Argitaratua: (1987)

The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule.
nork: Sattentau, Q, et al.
Argitaratua: (1988)

Functional epitope analysis of the human CD4 molecule. The MHC class II-dependent activation of resting T cells is inhibited by monoclonal antibodies to CD4 regardless whether or not they recognize epitopes involved in the binding of MHC class II or HIV gp120.
nork: Merkenschlager, M, et al.
Argitaratua: (1990)

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus.
nork: Dalgleish, A, et al.
Argitaratua: (1984)

CD4 activation of HIV fusion.
nork: Sattentau, Q
Argitaratua: (1992)

Idiotype vaccines for HIV based on CD4 antibodies
nork: Sattentau, Q, et al.
Argitaratua: (1990)

IDIOTYPE VACCINES FOR HIV BASED ON CD4 ANTIBODIES
nork: Sattentau, Q, et al.
Argitaratua: (1990)

Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
nork: Ramduth, D, et al.
Argitaratua: (2009)

The role of CD4 in HIV binding and entry.
nork: Sattentau, Q, et al.
Argitaratua: (1993)

HIV infection of CD45RA+ and CD45RO+ CD4+ T cells.
nork: Helbert, MR, et al.
Argitaratua: (1997)

Cellular and humoral antigenic epitopes in HIV and SIV.
nork: Nixon, D, et al.
Argitaratua: (1992)

CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.
nork: Kaul, R, et al.
Argitaratua: (2001)

Conservation of HIV-1 gp120 neutralizing epitopes after formalin inactivation.
nork: Sattentau, Q
Argitaratua: (1995)

A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells.
nork: Moore, J, et al.
Argitaratua: (1992)

Macrophage infection via selective capture of HIV-1-infected CD4+ T cells.
nork: Baxter, A, et al.
Argitaratua: (2014)

Interactions of HIV gp120 with the CD4 molecule on lymphocytes and in the nervous system.
nork: Sattentau, Q
Argitaratua: (1990)

INTERACTIONS OF HIV GP120 WITH THE CD4 MOLECULE ON LYMPHOCYTES AND IN THE NERVOUS-SYSTEM
nork: Sattentau, Q
Argitaratua: (1990)

Dissociation of gp120 from HIV-1 virions induced by soluble CD4.
nork: Moore, J, et al.
Argitaratua: (1990)

Epitope exposure on functional, oligomeric HIV-1 gp41 molecules.
nork: Sattentau, Q, et al.
Argitaratua: (1995)

Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes.
nork: Sattentau, Q, et al.
Argitaratua: (1989)

Selective HIV-1-induced downmodulation of CD4 and coreceptors.
nork: Chenine, A, et al.
Argitaratua: (2000)

Enhancement of soluble CD4-mediated HIV neutralization and gp 120 binding by CD4 autoantibodies and monoclonal antibodies.
nork: Moore, J, et al.
Argitaratua: (1990)

HIV infection and the immune system.
nork: Sattentau, Q
Argitaratua: (1989)

SOLUBLE CD4 BINDING TO HIV-1 VIRIONS CAUSES GP120 TO DISSOCIATE FROM GP41
nork: Moore, J, et al.
Argitaratua: (1991)

HIV Env induces the formation of supramolecular activation structures in CD4+ T cells
nork: Jolly, C, et al.
Argitaratua: (2002)

Cytomegalovirus (CMV) epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects
nork: Abana, CO, et al.
Argitaratua: (2017)

Identification of the residues in human CD4 critical for the binding of HIV.
nork: Arthos, J, et al.
Argitaratua: (1989)

Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific.
nork: Wilson, J, et al.
Argitaratua: (1998)

Altered CD4 interactions of HIV type 1 LAI variants selected for the capacity to induce membrane fusion in the presence of a monoclonal antibody to domain 2 of CD4.
nork: Klasse, P, et al.
Argitaratua: (1996)

HIV-Specific Antibodies Mediate Rapid Antibody-Dependent Cellular Cytotoxicity Against Primary HIV-Infected CD4+T Cells
nork: Smalls-Mantey, A, et al.
Argitaratua: (2010)

The Antiviral Efficacy of HIV-Specific CD8(+) T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate
nork: Ranasinghe, S, et al.
Argitaratua: (2011)

The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.
nork: Ranasinghe, SR, et al.
Argitaratua: (2011)

Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design.
nork: Kong, L, et al.
Argitaratua: (2012)

Meloidogyne incognita Surface Antigen Epitopes in Infected Arabidopsis Roots.
nork: Gravato-Nobre, M, et al.
Argitaratua: (1999)

Correlates of antibody-mediated protection against HIV infection.
nork: Sattentau, Q
Argitaratua: (2008)

Phagocytic uptake of transmitted/founder virus-infected CD4+T cells enhances macrophage infection
nork: Duncan, C, et al.
Argitaratua: (2012)

HIV-1-CD4-coreceptor interactions in virus binding and neutralization
nork: Sattentau, Q, et al.
Argitaratua: (1998)

CD8 epitope escape and reversion in acute HCV infection.
nork: Timm, J, et al.
Argitaratua: (2004)