Evidence that the large neutral amino acid L-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo.

L-Valine competes with tryptophan for transport into the brain and has previously been shown to decrease brain 5-HT synthesis. In the present study, the effect of L-valine on electrically evoked hippocampal 5-HT release was determined in the anaesthetized rat using microdialysis. In control animals...

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Hlavní autoři: Gartside, SE, Cowen, P, Sharp, T
Médium: Journal article
Jazyk:English
Vydáno: 1992

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