Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
Exosomes are nanovesicles released by virtually all cells, which act as intercellular messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes of cell uptake, and subcellular fate within recipient cells remain elusive. We quantitatively characterize exosome cell...
Main Authors: | Heusermann, W, Hean, J, Trojer, D, Steib, E, von Bueren, S, Graff-Meyer, A, Genoud, C, Martin, K, Pizzato, N, Voshol, J, Morrissey, D, Andaloussi, S, Wood, M, Meisner-Kober, N |
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Format: | Journal article |
Language: | English |
Published: |
Rockefeller University Press
2016
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