Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

Exosomes are nanovesicles released by virtually all cells, which act as intercellular messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes of cell uptake, and subcellular fate within recipient cells remain elusive. We quantitatively characterize exosome cell...

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Bibliographic Details
Main Authors: Heusermann, W, Hean, J, Trojer, D, Steib, E, von Bueren, S, Graff-Meyer, A, Genoud, C, Martin, K, Pizzato, N, Voshol, J, Morrissey, D, Andaloussi, S, Wood, M, Meisner-Kober, N
Format: Journal article
Language:English
Published: Rockefeller University Press 2016

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