Ataxia telangiectasia gene mutations in leukaemia and lymphoma.
Ataxia telangiectasia (AT) is a rare multisystem, autosomal, recessive disease characterised by neuronal degeneration, genome instability, and an increased risk of cancer. Approximately 10% of AT homozygotes develop cancer, mostly of the lymphoid system. Lymphoid malignancies in patients with AT are...
Autor principal: | Boultwood, J |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2001
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