Application of fast sensors to microscope mode spatial imaging mass spectrometry
The application of fast detectors to microscope mode spatial imaging mass spectrometry, in which the two-dimensional distributions of particular ion masses over a sample are projected onto a two-dimensional detector, allows the imaging of all mass peaks desorbed from a sample on each time-of-flight...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
IOP Publishing Ltd
2011
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| _version_ | 1826265496637407232 |
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| author | Brouard, M Johnsen, A Nomerotski, A Slater, C Vallance, C Yuen, W |
| author_facet | Brouard, M Johnsen, A Nomerotski, A Slater, C Vallance, C Yuen, W |
| author_sort | Brouard, M |
| collection | OXFORD |
| description | The application of fast detectors to microscope mode spatial imaging mass spectrometry, in which the two-dimensional distributions of particular ion masses over a sample are projected onto a two-dimensional detector, allows the imaging of all mass peaks desorbed from a sample on each time-of-flight cycle. Detecting all fragments per duty cycle means that fewer ionisation and acquisition cycles are required for a full set of data, leading to a reduction in overall detection time, amount of sample required, and sample degradation. Results from a proof-of-concept experiment, in which a fast frame transfer charge-coupled device camera (CCD) with 10 ns time resolution was coupled to a modified velocity-mapped imaging apparatus, are presented. © 2011 IOP Publishing Ltd and SISSA. |
| first_indexed | 2024-03-06T20:24:36Z |
| format | Journal article |
| id | oxford-uuid:2ef9c07c-c11e-42b4-b5d4-e3c200f42881 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:24:36Z |
| publishDate | 2011 |
| publisher | IOP Publishing Ltd |
| record_format | dspace |
| spelling | oxford-uuid:2ef9c07c-c11e-42b4-b5d4-e3c200f428812022-03-26T12:52:21ZApplication of fast sensors to microscope mode spatial imaging mass spectrometryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2ef9c07c-c11e-42b4-b5d4-e3c200f42881EnglishSymplectic Elements at OxfordIOP Publishing Ltd2011Brouard, MJohnsen, ANomerotski, ASlater, CVallance, CYuen, WThe application of fast detectors to microscope mode spatial imaging mass spectrometry, in which the two-dimensional distributions of particular ion masses over a sample are projected onto a two-dimensional detector, allows the imaging of all mass peaks desorbed from a sample on each time-of-flight cycle. Detecting all fragments per duty cycle means that fewer ionisation and acquisition cycles are required for a full set of data, leading to a reduction in overall detection time, amount of sample required, and sample degradation. Results from a proof-of-concept experiment, in which a fast frame transfer charge-coupled device camera (CCD) with 10 ns time resolution was coupled to a modified velocity-mapped imaging apparatus, are presented. © 2011 IOP Publishing Ltd and SISSA. |
| spellingShingle | Brouard, M Johnsen, A Nomerotski, A Slater, C Vallance, C Yuen, W Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title | Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title_full | Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title_fullStr | Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title_full_unstemmed | Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title_short | Application of fast sensors to microscope mode spatial imaging mass spectrometry |
| title_sort | application of fast sensors to microscope mode spatial imaging mass spectrometry |
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