Role of transfection in the priming of cytotoxic T-cells by DNA-mediated immunization.
DNA vaccination results in remarkably strong, broad-based immune responses to the encoded proteins and it is a simple and effective method of inducing cytotoxic T-lymphocyte (CTL) responses. Bone marrow-derived cells can take up and present exogenous antigenic protein liberated by transfected fibrob...
Main Authors: | Sbai, H, Schneider, J, Hill, A, Whalen, R |
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Format: | Journal article |
Language: | English |
Published: |
2002
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