The role of the physicochemical environment in determining disc cell behaviour.

The cells of the intervertebral disc exist in an unusual environment. They are embedded in a dense matrix containing a high concentration of aggrecan whose fixed negative charges regulate the extracellular ionic composition and osmolarity; both extracellular cation concentrations and osmolarity are...

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Bibliographic Details
Main Author: Urban, J
Format: Journal article
Language:English
Published: 2002