Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation
What is the optimal platelet count threshold for prophylactic platelet transfusions to minimize bleeding, platelet use, and adverse clinical outcomes in thrombocytopenic patients with hematological malignant neoplasms?Maintaining a higher platelet count threshold (≤20 × 109/L or ≤30 × 109/L) was not...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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American Medical Association
2016
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| _version_ | 1797061046462054400 |
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| author | Estcourt, L Stanworth, S Murphy, M |
| author_facet | Estcourt, L Stanworth, S Murphy, M |
| author_sort | Estcourt, L |
| collection | OXFORD |
| description | What is the optimal platelet count threshold for prophylactic platelet transfusions to minimize bleeding, platelet use, and adverse clinical outcomes in thrombocytopenic patients with hematological malignant neoplasms?Maintaining a higher platelet count threshold (≤20 × 109/L or ≤30 × 109/L) was not associated with less bleeding than the current standard (≤10 × 109/L), but required more platelet transfusions (low-quality evidence). |
| first_indexed | 2024-03-06T20:25:30Z |
| format | Journal article |
| id | oxford-uuid:2f40b071-2c05-4a97-b3c5-af07e7b10839 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:25:30Z |
| publishDate | 2016 |
| publisher | American Medical Association |
| record_format | dspace |
| spelling | oxford-uuid:2f40b071-2c05-4a97-b3c5-af07e7b108392022-03-26T12:54:10ZDifferent platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2f40b071-2c05-4a97-b3c5-af07e7b10839EnglishSymplectic Elements at OxfordAmerican Medical Association2016Estcourt, LStanworth, SMurphy, MWhat is the optimal platelet count threshold for prophylactic platelet transfusions to minimize bleeding, platelet use, and adverse clinical outcomes in thrombocytopenic patients with hematological malignant neoplasms?Maintaining a higher platelet count threshold (≤20 × 109/L or ≤30 × 109/L) was not associated with less bleeding than the current standard (≤10 × 109/L), but required more platelet transfusions (low-quality evidence). |
| spellingShingle | Estcourt, L Stanworth, S Murphy, M Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title | Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title_full | Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title_fullStr | Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title_full_unstemmed | Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title_short | Different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
| title_sort | different platelet count thresholds to guide use of prophylactic platelet transfusions for patients with hematological disorders after myelosuppressive chemotherapy or stem cell transplantation |
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