A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

Endotoxin tolerance is characterized by the suppression of further TNF release upon recurrent exposure to LPS. This phenomenon is proposed to act as a homeostatic mechanism preventing uncontrolled cytokine release such as that observed in bacterial sepsis. The regulatory mechanisms and interindividu...

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Chi tiết về thư mục
Những tác giả chính:	Fairfax, B, Davenport, E, Makino, S, Hill, A, Vannberg, F, Knight, J
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2011

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