A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.
Endotoxin tolerance is characterized by the suppression of further TNF release upon recurrent exposure to LPS. This phenomenon is proposed to act as a homeostatic mechanism preventing uncontrolled cytokine release such as that observed in bacterial sepsis. The regulatory mechanisms and interindividu...
| Główni autorzy: | , , , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
2011
|