QTL fine-mapping with recombinant-inbred heterogeneous stocks and in vitro heterogeneous stocks.
We compared strategies to fine-map Quantitative Trait Loci (QTL) in mice with heterogeneous stocks (HS). We showed that a panel of about 100 Recombinant Inbred Lines (RIL) derived from an HS, and which we called an RIHS, was ideally suited to fine-map QTL to very high resolution, without the cost of...
Main Authors: | Valdar, W, Flint, J, Mott, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2003
|
Similar Items
-
Simultaneous detection and fine mapping of quantitative trait loci in mice using heterogeneous stocks.
by: Mott, R, et al.
Published: (2002) -
High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues.
by: Huang, G, et al.
Published: (2009) -
Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice.
by: Valdar, W, et al.
Published: (2006) -
Mapping complex traits in heterogeneous stock mice
by: Flint, J
Published: (2008) -
Genome-wide genetic association of complex traits in heterogeneous stock mice.
by: Valdar, W, et al.
Published: (2006)