Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensit...
| Hoofdauteurs: | , , , , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
BioMed Central
2012
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| _version_ | 1826265587201867776 |
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| author | Färnert, A Ursing, J Tolfvenstam, T Rono, J Karlsson, L Sparrelid, E Lindegårdh, N |
| author_facet | Färnert, A Ursing, J Tolfvenstam, T Rono, J Karlsson, L Sparrelid, E Lindegårdh, N |
| author_sort | Färnert, A |
| collection | OXFORD |
| description | Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment. |
| first_indexed | 2024-03-06T20:26:00Z |
| format | Journal article |
| id | oxford-uuid:2f6b1c77-24b9-47d3-9c22-9f5b2e88a908 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:26:00Z |
| publishDate | 2012 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:2f6b1c77-24b9-47d3-9c22-9f5b2e88a9082022-03-26T12:55:13ZArtemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2f6b1c77-24b9-47d3-9c22-9f5b2e88a908EnglishSymplectic Elements at OxfordBioMed Central2012Färnert, AUrsing, JTolfvenstam, TRono, JKarlsson, LSparrelid, ELindegårdh, NArtemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment. |
| spellingShingle | Färnert, A Ursing, J Tolfvenstam, T Rono, J Karlsson, L Sparrelid, E Lindegårdh, N Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title | Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title_full | Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title_fullStr | Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title_full_unstemmed | Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title_short | Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. |
| title_sort | artemether lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with plasmodium falciparum malaria after returning from tanzania |
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