A pancreatic islet-specific microRNA regulates insulin secretion.

A pancreatic islet-specific microRNA regulates insulin secretion.

MicroRNAs (miRNAs) constitute a growing class of non-coding RNAs that are thought to regulate gene expression by translational repression. Several miRNAs in animals exhibit tissue-specific or developmental-stage-specific expression, indicating that they could play important roles in many biological...

Full description

Bibliographic Details
Main Authors:	Poy, M, Eliasson, L, Krutzfeldt, J, Kuwajima, S, Ma, X, Macdonald, P, Pfeffer, S, Tuschl, T, Rajewsky, N, Rorsman, P, Stoffel, M
Format:	Journal article
Language:	English
Published:	2004

Similar Items

Identification of a functional pancreatic b-cell-specific microRNA
by: Poy, M, et al.
Published: (2004)

Regulation of insulin secretion in human pancreatic islets.
by: Rorsman, P, et al.
Published: (2013)

Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells
by: Macdonald, P, et al.
Published: (2006)

Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.
by: MacDonald, P, et al.
Published: (2006)

Regulated exocytosis of single insulin granules and synaptic-like vesicles in membrane patches of insulin secreting cells
by: Macdonald, P, et al.
Published: (2004)

Role of microRNAs in the regulation of insulin secretion and during the development of type 2 diabetes
by: Lena Eliasson
Published: (2021-11-01)

Identification and characterization of single glucagon-secreting A-cells in a standard mouse islet preparation
by: Barg, S, et al.
Published: (1999)

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans.
by: Rorsman, P, et al.
Published: (2011)

Influence of the purification of human adult pancreatic islets on insulin secretion
by: Nikolić Dragan M., et al.
Published: (2010-01-01)

Patch-clamp characterisation of somatostatin-secreting -cells in intact mouse pancreatic islets.
by: Göpel, S, et al.
Published: (2000)

Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.
by: Patrick E MacDonald, et al.
Published: (2006-02-01)

Calcium increases endocytotic vesicle size and accelerates membrane fission in insulin-secreting INS-1 cells.
by: MacDonald, P, et al.
Published: (2005)

MicroRNA-7a regulates pancreatic β cell function.
by: Latreille, M, et al.
Published: (2014)

Effect of hypoxia on insulin secretion and viability of pancreatic islet tissue
by: Dionne, Keith Evan
Published: (2005)

Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets
by: Uma D. Kabra, et al.
Published: (2021-06-01)

Effect of alcohol on insulin secretion and viability of human pancreatic islets
by: Nikolić Dragan, et al.
Published: (2017-01-01)

Insulin secretion: Function and therapy of pancreatic beta-cells in diabetes
by: Rorsman, P
Published: (2005)

COOLING INHIBITS INSULIN-SECRETION BY SUPPRESSION OF GRANULE MOBILIZATION
by: Eliasson, L, et al.
Published: (1995)

Components of insulin secretion: lessons to be learnt from capacitance.
by: Rorsman, P, et al.
Published: (1997)

Fast exocytosis with few Ca2+-channels by economical use of Ca2+ in insulin-secreting pancreatic B-cells
by: Barg, S, et al.
Published: (2000)

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells.
by: Olofsson, C, et al.
Published: (2002)

Restructuring of pancreatic islets and insulin secretion in a postnatal critical window.
by: Cristina Aguayo-Mazzucato, et al.
Published: (2006-12-01)

The Cell Physiology of Biphasic Insulin Secretion.
by: Rorsman, P, et al.
Published: (2000)

Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat.
by: Jonathan Lou S Esguerra, et al.
Published: (2011-01-01)

Pancreatic β-cell electrical activity and insulin secretion: of mice and men
by: Rorsman, P, et al.
Published: (2017)

Eugenol Improves Insulin Secretion and Content of Pancreatic Islets from Male Mouse
by: Ali Akbar Oroojan
Published: (2020-01-01)

In Vitro Study of Insulin Secretion from Mouse Pancreatic Islets-Siriraj Experiences
by: Suwattanee Kooptiwut, et al.
Published: (2005-01-01)

Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets
by: Yi Cheng, et al.
Published: (2023-11-01)

Dynamics and Regulation of Insulin Secretion in Pancreatic Islets from Normal Young Children.
by: Jean-Claude Henquin, et al.
Published: (2016-01-01)

Cellular function in multicellular system for hormone-secretion: electrophysiological aspect of studies on alpha-, beta- and delta-cells of the pancreatic islet.
by: Kanno, T, et al.
Published: (2002)

Gap junction conductance in pancreatic islets
by: Gopel, S, et al.
Published: (2000)

The DPP-IV inhibitor, sitgliptin enhances glucose-stimulated insulin secretion from mouse isolated islets
by: Clark, A, et al.
Published: (2013)

Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets
by: Valia Bravo-Egana, et al.
Published: (2012-01-01)

Novel aspects of the molecular mechanisms controlling insulin secretion.
by: Eliasson, L, et al.
Published: (2008)

11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets.
by: Swali, A, et al.
Published: (2008)

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes
by: Tina Rönn, et al.
Published: (2023-12-01)

Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans.
by: Zhang, Q, et al.
Published: (2008)

Ion channels, electrical activity and insulin secretion.
by: Rorsman, P, et al.
Published: (1994)

Exocytosis study of beta- and alpha-cells in intact pancreatic islets using capacitance measurement
by: Zhang, Q, et al.
Published: (2004)

MicroRNAs as stress regulators in pancreatic beta cells and diabetes
by: Mary P. LaPierre, et al.
Published: (2017-09-01)