Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion.
Abnormal serotonergic function is implicated in the pathogenesis of affective disorders. We induced transient depressive relapses in volunteer patients by rapidly depleting plasma tryptophan, the precursor of serotonin (5-HT), and measured neural activity during different cognitive tasks using posit...
Main Authors: | Morris, J, Smith, K, Cowen, P, Friston, K, Dolan, R |
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Format: | Journal article |
Language: | English |
Published: |
1999
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