Functional characterization of CD8(+) antigen-specific cytotoxic T lymphocytes after enrichment based on cytokine secretion: comparison with the MHC-tetramer technology.

Functional characterization of CD8(+) antigen-specific cytotoxic T lymphocytes after enrichment based on cytokine secretion: comparison with the MHC-tetramer technology.

Cell therapy with antigen-specific T cells holds promise for various diseases including cancer and viral infections. The powerful enrichment procedure based on major histocompatibility complex (MHC)-tetramers, however, is of limited applicability so far. Therefore, the recently developed cell surfac...

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Bibliographic Details
Main Authors:	Oelke, M, Kurokawa, T, Hentrich, I, Behringer, D, Cerundolo, V, Lindemann, A, Mackensen, A
Format:	Journal article
Language:	English
Published:	2000

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