Endothelin: an important factor in acute renal failure?
Very low concentrations of the vasoconstrictor peptide endothelin cause intense long-lasting renal vasoconstriction. In the isolated perfused rat kidney, the concentration of endothelin required to reduce blood-flow by 50% is 200 pmol/l, compared with 1000 pmol/l angiotensin II (previously the most...
Main Authors: | Firth, J, Ratcliffe, P, Raine, A, Ledingham, J |
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Format: | Journal article |
Language: | English |
Published: |
1988
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