Endothelin: an important factor in acute renal failure?

Very low concentrations of the vasoconstrictor peptide endothelin cause intense long-lasting renal vasoconstriction. In the isolated perfused rat kidney, the concentration of endothelin required to reduce blood-flow by 50% is 200 pmol/l, compared with 1000 pmol/l angiotensin II (previously the most...

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Bibliographic Details
Main Authors: Firth, J, Ratcliffe, P, Raine, A, Ledingham, J
Format: Journal article
Language:English
Published: 1988

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