Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection.
It has been shown that certain pathogens can trigger efficient T cell responses in the absence of CD28, a key costimulatory receptor expressed on resting T cells. Inducible costimulator protein (ICOS) is an inducible costimulator structurally and functionally related to CD28. Here, we show that in t...
Main Authors: | Kopf, M, Coyle, A, Schmitz, N, Barner, M, Oxenius, A, Gallimore, A, Gutierrez-Ramos, J, Bachmann, M |
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Format: | Journal article |
Language: | English |
Published: |
2000
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