IV and oral fosfomycin pharmacokinetics in neonates with suspected clinical sepsis

Background Fosfomycin has the potential to be re-purposed as part of a combination therapy to treat neonatal sepsis where resistance to current standard of care (SOC) is common. Limited data exist on neonatal fosfomycin pharmacokinetics and estimates of bioavailability and CSF/plasma ratio in this v...

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Main Authors: Kane, Z, Gastine, S, Obiero, C, Williams, P, Murunga, S, Thitiri, J, Ellis, S, Correia, E, Nyaoke, B, Kipper, K, van den Anker, J, Sharland, M, Berkley, JA, Standing, JF
格式: Journal article
語言:English
出版: Oxford University Press 2021