Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.

Tuberculosis (TB) continues to be a major global health disaster, despite the widespread use of BCG and effective drug therapies. The development of an efficacious new TB vaccine would be an important component of disease control in the future. Many approaches are being utilised to enhance understan...

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Hlavní autoři: Sander, C, Mcshane, H
Médium: Journal article
Jazyk:English
Vydáno: 2007
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author Sander, C
Mcshane, H
author_facet Sander, C
Mcshane, H
author_sort Sander, C
collection OXFORD
description Tuberculosis (TB) continues to be a major global health disaster, despite the widespread use of BCG and effective drug therapies. The development of an efficacious new TB vaccine would be an important component of disease control in the future. Many approaches are being utilised to enhance understanding of the requirements of a successful vaccine. Numerous vaccines are being designed and assessed in a series of animal models, with a few progressing to clinical trials. Here, the steps involved in the development and evaluation of TB vaccines will be discussed, including description of the most frequently used animal models and the processes involved in advancing vaccines to phase III trials.
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spelling oxford-uuid:2fb994fb-6c7e-4c44-af04-1f1d7d7fda5c2022-03-26T12:57:05ZTranslational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2fb994fb-6c7e-4c44-af04-1f1d7d7fda5cEnglishSymplectic Elements at Oxford2007Sander, CMcshane, HTuberculosis (TB) continues to be a major global health disaster, despite the widespread use of BCG and effective drug therapies. The development of an efficacious new TB vaccine would be an important component of disease control in the future. Many approaches are being utilised to enhance understanding of the requirements of a successful vaccine. Numerous vaccines are being designed and assessed in a series of animal models, with a few progressing to clinical trials. Here, the steps involved in the development and evaluation of TB vaccines will be discussed, including description of the most frequently used animal models and the processes involved in advancing vaccines to phase III trials.
spellingShingle Sander, C
Mcshane, H
Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title_full Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title_fullStr Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title_full_unstemmed Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title_short Translational mini-review series on vaccines: Development and evaluation of improved vaccines against tuberculosis.
title_sort translational mini review series on vaccines development and evaluation of improved vaccines against tuberculosis
work_keys_str_mv AT sanderc translationalminireviewseriesonvaccinesdevelopmentandevaluationofimprovedvaccinesagainsttuberculosis
AT mcshaneh translationalminireviewseriesonvaccinesdevelopmentandevaluationofimprovedvaccinesagainsttuberculosis