Platelet PECAM-1 inhibits thrombus formation in vivo.

Platelet PECAM-1 inhibits thrombus formation in vivo.

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a cell surface glycoprotein receptor expressed on a range of blood cells, including platelets, and on vascular endothelial cells. PECAM-1 possesses adhesive and signaling properties, the latter being mediated by immunoreceptor tyrosine-based...

Full description

Bibliographic Details
Main Authors:	Falati, S, Patil, S, Gross, P, Stapleton, M, Merrill-Skoloff, G, Barrett, N, Pixton, K, Weiler, H, Cooley, B, Newman, D, Newman, P, Furie, B, Gibbins, J
Format:	Journal article
Language:	English
Published:	2006

Similar Items

Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B
by: Eva M Soriano Jerez, et al.
Published: (2021-08-01)

Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation.
by: Jones, S, et al.
Published: (2008)

A Role for Peripheral Tachykinins and the Neurokinin 1 Receptor in the Regulation of Platelet Thrombus Formation
by: Jones, S, et al.
Published: (2008)

Haemodynamics regulate fibronectin assembly via PECAM
by: Chen, Z, et al.
Published: (2017)

Aдpecam в языковой коммуникации
by: Н. И. ФОРМАНОВСKАЯ
Published: (2021-05-01)

PECAM-1/Thrombus Ratio Correlates with Blood Loss during Off-Pump Coronary Artery Bypass Grafting (OPCAB) Surgery: A Preliminary Study
by: Natalia Bielicka, et al.
Published: (2023-08-01)

I15 Targeting type I interferon in SLE and lupus nephritis
by: Richard Furie
Published: (2024-03-01)

29 Plasmacytoid dendritic cells as a treatment target
by: Richard Furie
Published: (2023-09-01)

09 Herpes zoster prevalence and recommendations from clinical trial safety data
by: Richard Furie
Published: (2023-09-01)

The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus.
by: Hansson, K, et al.
Published: (2004)

Role of platelet endothelial adhesion molecule (PECAM)-1 in sensing and mediating high temporal gradients of shear stress in arterioles
by: Koller, A, et al.
Published: (2006)

The bile acid receptor TGR5 inhibits platelet activation and thrombus formation
by: Friedrich Reusswig, et al.
Published: (2024-12-01)

Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses
by: Merideth Early, et al.
Published: (2017-07-01)

Soluble Pecam-1 as a Biomarker in Periprosthetic Joint Infection
by: Michael Fuchs, et al.
Published: (2021-02-01)

Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan
by: Isabella Provenzale, et al.
Published: (2023-08-01)

Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo
by: Madeleine Goeritzer, et al.
Published: (2022-03-01)

PECAM1 plays a role in the pathogenesis and treatment of bone metastases
by: Zhuo-Tao Liang, et al.
Published: (2023-03-01)

Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction
by: Amanda J. Unsworth, et al.
Published: (2019-08-01)

Thioredoxin inhibitors attenuate platelet function and thrombus formation
by: Metcalfe, C, et al.
Published: (2016)

The Total Thrombus Formation (T-TAS) platelet (PL) assay, a novel test that evaluates whole blood platelet thrombus formation under physiological conditions
by: K.L. Zheng, et al.
Published: (2022-02-01)

Platelets and megakaryocytes /
by: Gibbins, Jonathan M., et al.
Published: (c200)

Binding of Plasmodium falciparum-infected erythrocytes to soluble platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): frequent recognition by clinical isolates.
by: Heddini, A, et al.
Published: (2001)

PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress.
by: Bagi, Z, et al.
Published: (2005)

Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension
by: Aleksandra Gąsecka, et al.
Published: (2021-03-01)

Sanguinarine Attenuates Collagen-Induced Platelet Activation and Thrombus Formation
by: Dan Shu, et al.
Published: (2021-04-01)

Modern concepts of the role of platelet receptors in the dynamics of thrombus formation
by: I. Nikolaieva, et al.
Published: (2016-07-01)

PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing
by: Eulashini Chuntharpursat-Bon, et al.
Published: (2023-04-01)

The contribution of non-structrual components to the overall dynamic behaviour of concrete floor slabs
by: Falati, S, et al.
Published: (1999)

Platelets and their Role in Thrombotic and Cardiovascular Disease: The Impact of Proteomic Analysis
by: Stanley, R, et al.
Published: (2011)

Are Mean Platelet Volume and Platelet Count Associated with Presence of Thrombus in Patients with Abdominal Aortic Aneursym?
by: Mehmet Toptaş, et al.
Published: (2018-03-01)

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo
by: Amro Elgheznawy, et al.
Published: (2023-06-01)

Reduced sensitivity wall shear stress in arterioles of PECAM knockout mice due to impaired mechanotransduction
by: Bagi, Z, et al.
Published: (2004)

Development of A New Mouse Model for Intrahepatic Cholangiocellular Carcinoma: Accelerating Functions of Pecam-1
by: Ihtzaz Ahmed Malik, et al.
Published: (2019-07-01)

Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation
by: Lisa Maria Metz, et al.
Published: (2022-05-01)

Effect of platelet inhibitors on thrombus burden in patients with acute pulmonary embolism
by: Joseph Van Galen, et al.
Published: (2021-01-01)

1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis
by: Kahdr A. Alatawi, et al.
Published: (2021-10-01)

Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein ib via AKT/glycogen synthase kinase-3/dynamin and integrin αiibβ3
by: Jones, C, et al.
Published: (2014)

Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.
by: Jones, C, et al.
Published: (2014)

PECAM-1 Is Down-Regulated in γδT Cells during Remission, but Up-Regulated in Relapse of Multiple Sclerosis
by: Michał K. Zarobkiewicz, et al.
Published: (2022-06-01)

Future innovations in anti-platelet therapies.
by: Barrett, N, et al.
Published: (2008)