Analysis of nucleotide synthesis and homologous recombination repair in Schizosaccharomyces pombe

<p>Nucleotide synthesis is a conserved and highly regulated response to DNA damage, required for the efficient repair of DNA double strand breaks (DSB) by homologous recombination (HR). This is essential to prevent loss of heterozygosity (LOH) and maintain genome stability. The aim of this stu...

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Bibliographic Details
Main Author: Blaikley, E
Other Authors: Humphrey, T
Format: Thesis
Language:English
Published: 2014
Subjects: