Inhibition of Apoptosis and NF-kappa B Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

Inhibition of Apoptosis and NF-kappa B Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

Vaccinia virus (VACV) protein N1 is an intracellular virulence factor and belongs to a family of VACV B-cell lymphoma (Bcl)-2-like proteins whose members inhibit apoptosis or activation of pro-inflammatory transcription factors, such as interferon (IFN) regulatory factor-3 (IRF-3) and nuclear factor...

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Bibliographic Details
Main Authors:	de Motes, C, Cooray, S, Ren, H, Almeida, G, McGourty, K, Bahar, M, Stuart, D, Grimes, J, Graham, S, Smith, G
Format:	Journal article
Published:	2011

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