Targeting the ubiquitylation and ISGylation machinery for the treatment of COVID-19

Ubiquitylation and ISGylation are protein post-translational modifications (PTMs) and two of the main events involved in the activation of pattern recognition receptor (PRRs) signals allowing the host defense response to viruses. As with similar viruses, SARS-CoV-2, the virus causing COVID-19, hijac...

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Bibliographic Details
Main Authors: Vere, G, Alam, MR, Farrar, S, Kealy, R, Kessler, BM, O’Brien, DP, Pinto-Fernández, A
Format: Journal article
Language:English
Published: MDPI 2022