Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis
<p><strong>OBJECTIVE:</strong> The Patient Reported Outcome Measurement Information System (PROMIS) is a collection of item banks of self-reported health. This study assessed the feasibility and construct validity of using PROMIS instruments in vasculitis.</p> <p><st...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Journal of Rheumatology Publishing Co Ltd
2019
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| _version_ | 1797061213466656768 |
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| author | Tomasson, G Farrar, JT Cuthbertson, D McAlear, CA Ashdown, S Cronholm, PF Dawson, J Gebhart, D Lanier, G Luqmani, RA Milman, N Peck, J Robson, JC Shea, JA Carette, S Khalidi, N Koening, CL Langford, CA Monach, PA Moreland, L Pagnoux, C Specks, U Sreih, AG Ytterberg, SR Merkel, PA Vasculitis Clinical Research Consortium |
| author_facet | Tomasson, G Farrar, JT Cuthbertson, D McAlear, CA Ashdown, S Cronholm, PF Dawson, J Gebhart, D Lanier, G Luqmani, RA Milman, N Peck, J Robson, JC Shea, JA Carette, S Khalidi, N Koening, CL Langford, CA Monach, PA Moreland, L Pagnoux, C Specks, U Sreih, AG Ytterberg, SR Merkel, PA Vasculitis Clinical Research Consortium |
| author_sort | Tomasson, G |
| collection | OXFORD |
| description | <p><strong>OBJECTIVE:</strong> The Patient Reported Outcome Measurement Information System (PROMIS) is a collection of item banks of self-reported health. This study assessed the feasibility and construct validity of using PROMIS instruments in vasculitis.</p> <p><strong>METHODS:</strong> Data from a multicenter longitudinal cohort of subjects with systemic vasculitis were used. Instruments from 10 PROMIS item banks were selected with direct involvement of patients. Subjects completed PROMIS instruments using computer adaptive testing (CAT). The Short Form 36 (SF-36) was also administered. Cross-sectional construct validity was assessed by calculating correlations of PROMIS scores with SF-36 measures and physician- and patient global scores for disease activity. Longitudinal construct validity was assessed by correlations of between-visit differences in PROMIS scores with differences in other measures.</p> <p><strong>RESULTS:</strong> During the study period 973 subjects came for 2,306 study visits and the PROMIS collection was completed at 2,276 (99%) of visits. The median time needed to complete each PROMIS instrument ranged from 40-55 seconds. PROMIS instruments correlated crosssectionally with individual scales of the SF-36, most strongly with subscales of the SF-36 addressing the same domain as the PROMIS instrument. For example, PROMIS Fatigue correlated with both the Physical Component Score (PCS) (r=-0.65) and with the Mental Component Score (MCS) (r=-0.54). PROMIS Physical Function correlated strongly with PCS (r=0.81) but weakly with MCS (r=0.29). Weaker correlations were obse¬rved longitudinally between change in PROMIS scores with change in PCS and MCS.</p> <p><strong>CONCLUSION:</strong> Collection of data using CAT PROMIS instruments is feasible among patients with vasculitis and has some cross-sectional and longitudinal construct validity.</p> |
| first_indexed | 2024-03-06T20:27:51Z |
| format | Journal article |
| id | oxford-uuid:2fff8454-e3d5-4647-8648-84f8ff9c7d41 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:27:51Z |
| publishDate | 2019 |
| publisher | Journal of Rheumatology Publishing Co Ltd |
| record_format | dspace |
| spelling | oxford-uuid:2fff8454-e3d5-4647-8648-84f8ff9c7d412022-03-26T12:59:04ZFeasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2fff8454-e3d5-4647-8648-84f8ff9c7d41EnglishSymplectic Elements at OxfordJournal of Rheumatology Publishing Co Ltd2019Tomasson, GFarrar, JTCuthbertson, DMcAlear, CAAshdown, SCronholm, PFDawson, JGebhart, DLanier, GLuqmani, RAMilman, NPeck, JRobson, JCShea, JACarette, SKhalidi, NKoening, CLLangford, CAMonach, PAMoreland, LPagnoux, CSpecks, USreih, AGYtterberg, SRMerkel, PAVasculitis Clinical Research Consortium<p><strong>OBJECTIVE:</strong> The Patient Reported Outcome Measurement Information System (PROMIS) is a collection of item banks of self-reported health. This study assessed the feasibility and construct validity of using PROMIS instruments in vasculitis.</p> <p><strong>METHODS:</strong> Data from a multicenter longitudinal cohort of subjects with systemic vasculitis were used. Instruments from 10 PROMIS item banks were selected with direct involvement of patients. Subjects completed PROMIS instruments using computer adaptive testing (CAT). The Short Form 36 (SF-36) was also administered. Cross-sectional construct validity was assessed by calculating correlations of PROMIS scores with SF-36 measures and physician- and patient global scores for disease activity. Longitudinal construct validity was assessed by correlations of between-visit differences in PROMIS scores with differences in other measures.</p> <p><strong>RESULTS:</strong> During the study period 973 subjects came for 2,306 study visits and the PROMIS collection was completed at 2,276 (99%) of visits. The median time needed to complete each PROMIS instrument ranged from 40-55 seconds. PROMIS instruments correlated crosssectionally with individual scales of the SF-36, most strongly with subscales of the SF-36 addressing the same domain as the PROMIS instrument. For example, PROMIS Fatigue correlated with both the Physical Component Score (PCS) (r=-0.65) and with the Mental Component Score (MCS) (r=-0.54). PROMIS Physical Function correlated strongly with PCS (r=0.81) but weakly with MCS (r=0.29). Weaker correlations were obse¬rved longitudinally between change in PROMIS scores with change in PCS and MCS.</p> <p><strong>CONCLUSION:</strong> Collection of data using CAT PROMIS instruments is feasible among patients with vasculitis and has some cross-sectional and longitudinal construct validity.</p> |
| spellingShingle | Tomasson, G Farrar, JT Cuthbertson, D McAlear, CA Ashdown, S Cronholm, PF Dawson, J Gebhart, D Lanier, G Luqmani, RA Milman, N Peck, J Robson, JC Shea, JA Carette, S Khalidi, N Koening, CL Langford, CA Monach, PA Moreland, L Pagnoux, C Specks, U Sreih, AG Ytterberg, SR Merkel, PA Vasculitis Clinical Research Consortium Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title | Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title_full | Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title_fullStr | Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title_full_unstemmed | Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title_short | Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
| title_sort | feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis |
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