Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibition with statins.

SIGNIFICANCE: Atrial fibrillation (AF) is a burgeoning health-care problem, and the currently available therapeutic armamentarium is barely efficient. Experimental and clinical evidence implicates inflammation and myocardial oxidative stress in the pathogenesis of AF. RECENT ADVANCES: Local and syst...

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Autori principali: Pinho-Gomes, A, Reilly, S, Brandes, R, Casadei, B
Natura: Journal article
Lingua:English
Pubblicazione: 2014