Immunology taught by rats

<p>Immunology may be best taught by viruses, and possibly by humans, but the rats of New York City surprisingly also have plenty to offer. A survey published in 2014 of the pathogens carried by rats trapped in houses and parks in Manhattan identified a huge burden of infectious agents in thes...

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Main Authors: Klenerman, P, Barnes, E
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2017
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author Klenerman, P
Barnes, E
author_facet Klenerman, P
Barnes, E
author_sort Klenerman, P
collection OXFORD
description <p>Immunology may be best taught by viruses, and possibly by humans, but the rats of New York City surprisingly also have plenty to offer. A survey published in 2014 of the pathogens carried by rats trapped in houses and parks in Manhattan identified a huge burden of infectious agents in these animals, including several novel viruses. Among these are Norway rat hepaciviruses (NrHVs), which belong to the same family as hepatitis C virus (HCV). NrHVs were found in rat livers, raising the possibility of establishing a small animal model of human HCV infection. On page 204 of this issue, Billerbeck et al. fulfill this prediction.</p>
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spelling oxford-uuid:301fd12a-7f65-4710-994c-b4825d3b897f2022-03-26T12:59:38ZImmunology taught by ratsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:301fd12a-7f65-4710-994c-b4825d3b897fEnglishSymplectic Elements at OxfordAmerican Association for the Advancement of Science2017Klenerman, PBarnes, E <p>Immunology may be best taught by viruses, and possibly by humans, but the rats of New York City surprisingly also have plenty to offer. A survey published in 2014 of the pathogens carried by rats trapped in houses and parks in Manhattan identified a huge burden of infectious agents in these animals, including several novel viruses. Among these are Norway rat hepaciviruses (NrHVs), which belong to the same family as hepatitis C virus (HCV). NrHVs were found in rat livers, raising the possibility of establishing a small animal model of human HCV infection. On page 204 of this issue, Billerbeck et al. fulfill this prediction.</p>
spellingShingle Klenerman, P
Barnes, E
Immunology taught by rats
title Immunology taught by rats
title_full Immunology taught by rats
title_fullStr Immunology taught by rats
title_full_unstemmed Immunology taught by rats
title_short Immunology taught by rats
title_sort immunology taught by rats
work_keys_str_mv AT klenermanp immunologytaughtbyrats
AT barnese immunologytaughtbyrats