The phytocannabinoid Δ9‐tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum

The phytocannabinoid Δ9‐tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum

<br><strong>Background and purpose: </strong>The phytocannabinoid Δ9‐tetrahydrocannabivarin (Δ9‐THCV) has been reported to exhibit a diverse pharmacology; here, we investigate functional effects of Δ9‐THCV, extracted from Cannabis sativa, using electrophysiological techniques to de...

Full description

Bibliographic Details
Main Authors:	Ma, Y-L, Weston, SE, Whalley, BJ, Stephens, GJ
Format:	Journal article
Language:	English
Published:	Wiley 2009

Similar Items

Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin
by: Arthur Neuberger, et al.
Published: (2023-08-01)

Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice
by: Verena Untiet, et al.
Published: (2023-04-01)

Antibacterial Effects of Phytocannabinoids
by: Cassidy Scott, et al.
Published: (2022-09-01)

Phytocannabinoids in the Pharmacotherapy of Psoriasis
by: Adam Wroński, et al.
Published: (2023-01-01)

Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia
by: Yaiza M. Arenas, et al.
Published: (2022-10-01)

Behavioral and Pharmacokinetic Profile of Indole-Derived Synthetic Cannabinoids JWH-073 and JWH-210 as Compared to the Phytocannabinoid Δ9-THC in Rats
by: Libor Uttl, et al.
Published: (2018-10-01)

Esmolol modulates inhibitory neurotransmission in the substantia gelatinosa of the spinal trigeminal nucleus of the rat
by: Kato Fusao, et al.
Published: (2011-09-01)

Glycine receptor autoantibodies disrupt inhibitory neurotransmission
by: Crisp, SJ, et al.
Published: (2019)

High fat-fed GPR55 null mice display impaired glucose tolerance without concomitant changes in energy balance or insulin sensitivity but are less responsive to the effects of the cannabinoids rimonabant or Δ(9)-tetrahydrocannabivarin on weight gain
by: Edward T. Wargent, et al.
Published: (2020-08-01)

Beyond CBD: Inhibitory effects of lesser studied phytocannabinoids on human voltage-gated sodium channels
by: Carol J. Milligan, et al.
Published: (2023-02-01)

Spontaneous and evoked neurotransmission are partially segregated at inhibitory synapses
by: Patricia M Horvath, et al.
Published: (2020-05-01)

Phytocannabinoids, the Endocannabinoid System and Male Reproduction
by: Jinhwan Lim, et al.
Published: (2023-01-01)

Inhibitory neurotransmission drives endocannabinoid degradation to promote memory consolidation
by: Christophe J. Dubois, et al.
Published: (2020-12-01)

Biosynthesis of Phytocannabinoids and Structural Insights: A Review
by: Rasiravathanahalli Kaveriyappan Govindarajan, et al.
Published: (2023-03-01)

Therapeutic Potential of Phytocannabinoid Cannabigerol for Multiple Sclerosis: Modulation of Microglial Activation In Vitro and In Vivo
by: Sigal Fleisher-Berkovich, et al.
Published: (2023-02-01)

The Biochemistry of Phytocannabinoids and Metabolic Engineering of Their Production in Heterologous Systems
by: Kaitlyn Blatt-Janmaat, et al.
Published: (2021-02-01)

Phytocannabinoids: Chromatographic Screening of Cannabinoids and Loading into Lipid Nanoparticles
by: Aleksandra Zielińska, et al.
Published: (2023-03-01)

Phytocannabinoids Biosynthesis in Angiosperms, Fungi, and Liverworts and Their Versatile Role
by: Yamshi Arif, et al.
Published: (2021-06-01)

An Evaluation of Understudied Phytocannabinoids and Their Effects in Two Neuronal Models
by: Alex Straiker, et al.
Published: (2021-09-01)

Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes
by: Camilla Di Meo, et al.
Published: (2022-05-01)

Phytocannabinoids: Pharmacological effects, biomedical applications, and worldwide prospection
by: Ana L.G. de Brito Siqueira, et al.
Published: (2023-11-01)

Tetrahydrocannabivarin (THCV) Protects Adipose-Derived Mesenchymal Stem Cells (ASC) against Endoplasmic Reticulum Stress Development and Reduces Inflammation during Adipogenesis
by: Anna Kowalczuk, et al.
Published: (2023-04-01)

GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol
by: Gabriele Ruffolo, et al.
Published: (2022-12-01)

Author Correction: Inhibitory neurotransmission drives endocannabinoid degradation to promote memory consolidation
by: Christophe J. Dubois, et al.
Published: (2021-02-01)

Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway
by: Yaiza M. Arenas, et al.
Published: (2020-09-01)

Epicutaneous Sensitization to the Phytocannabinoid β-Caryophyllene Induces Pruritic Inflammation
by: Saadet Inan, et al.
Published: (2023-09-01)

Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy
by: Lara Senn, et al.
Published: (2020-07-01)

The anticonvulsant phytocannabinoids CBGVA and CBDVA inhibit recombinant T-type channels
by: Michael Udoh, et al.
Published: (2022-11-01)

Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol
by: Patrycja Bielawiec, et al.
Published: (2020-03-01)

Hydrogen sulfide plays a key role in the inhibitory neurotransmission to the pig intravesical ureter.
by: Vítor S Fernandes, et al.
Published: (2014-01-01)

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission
by: Ingrid eChamma, et al.
Published: (2012-02-01)

Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission
by: Maria Nicol Colombo, et al.
Published: (2019-08-01)

Extrasynaptic neurotransmission as a way of modulating neuronal functions.
by: Francisco Fernandez De-Miguel, et al.
Published: (2012-02-01)

Modulation of Noradrenergic Neurotransmission in Isolated Rat Radial Artery
by: Ana Cristina Martínez, et al.
Published: (2009-01-01)

Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia
by: Paula P.M. de, et al.
Published: (2004-01-01)

Treatment of malignant diseases with phytocannabinoids: promising observations in animal models and patients
by: Gerhard Nahler
Published: (2023-12-01)

Phytocannabinoids Reduce Seizures in Larval Zebrafish and Affect Endocannabinoid Gene Expression
by: Roshni Kollipara, et al.
Published: (2023-09-01)

Interaction of Glia Cells with Glioblastoma and Melanoma Cells under the Influence of Phytocannabinoids
by: Urszula Hohmann, et al.
Published: (2022-01-01)

Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts
by: Marta Gerasymchuk, et al.
Published: (2022-12-01)

Anti-Microbial Activity of Phytocannabinoids and Endocannabinoids in the Light of Their Physiological and Pathophysiological Roles
by: Ronit Vogt Sionov, et al.
Published: (2022-03-01)