Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies.

Míreanna comhchosúla

• Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.
  de réir: Esnouf, R, et al.
  Foilsithe / Cruthaithe: (1995)
• Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.
  de réir: Ren, J, et al.
  Foilsithe / Cruthaithe: (2008)
• Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
  de réir: Hopkins, A, et al.
  Foilsithe / Cruthaithe: (2004)
• Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
  de réir: Ren, J, et al.
  Foilsithe / Cruthaithe: (2000)
• Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
  de réir: Hopkins, A, et al.
  Foilsithe / Cruthaithe: (1996)