Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

T cell cross-reactivity ensures that diverse pathogen-derived epitopes encountered during a lifetime are recognized by the available TCR repertoire. A feature of cross-reactivity where previous exposure to one microbe can alter immunity to subsequent, non-related pathogens has been mainly explored f...

Full description

Bibliographic Details
Main Authors: Mendoza, JL, Fischer, S, Gee, MH, Lam, LH, Brackenridge, S, Powrie, FM, Birnbaum, M, McMichael, AJ, Garcia, KC, Gillespie, GM
Format: Journal article
Language:English
Published: eLife Sciences Publications, Ltd 2020