Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
T cell cross-reactivity ensures that diverse pathogen-derived epitopes encountered during a lifetime are recognized by the available TCR repertoire. A feature of cross-reactivity where previous exposure to one microbe can alter immunity to subsequent, non-related pathogens has been mainly explored f...
Main Authors: | Mendoza, JL, Fischer, S, Gee, MH, Lam, LH, Brackenridge, S, Powrie, FM, Birnbaum, M, McMichael, AJ, Garcia, KC, Gillespie, GM |
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Format: | Journal article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2020
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