Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators.

Ижил төстэй зүйлс

• NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
  -н: Smith, C, зэрэг
  Хэвлэсэн: (2001)
• Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
  -н: Feldmann, M, зэрэг
  Хэвлэсэн: (2002)
• Antigen-specific T-cell downregulation by human dendritic cells following blockade of NF-kappaB.
  -н: Calder, V, зэрэг
  Хэвлэсэн: (2003)
• Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines.
  -н: Yoshimura, S, зэрэг
  Хэвлэсэн: (2001)
• Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
  -н: Andreakos, E, зэрэг
  Хэвлэсэн: (2006)