Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Show other versions (1)

Through genome-wide association meta-analyses of up to 133,010 individuals of European ancestry without diabetes, including individuals newly genotyped using the Metabochip, we have increased the number of confirmed loci influencing glycemic traits to 53, of which 33 also increase type 2 diabetes ri...

Full description

Bibliographic Details
Main Authors:	Scott, R, Lagou, V, Welch, R, Wheeler, E, Montasser, M, Luan, J, MäGi, R, Strawbridge, R, Rehnberg, E, Gustafsson, S, Kanoni, S, Rasmussen-Torvik, L, Yengo, L, Lecoeur, C, Shungin, D, Sanna, S
Format:	Journal article
Published:	2012

Similar Items

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
by: Scott, R, et al.
Published: (2012)

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
by: Manning, A, et al.
Published: (2012)

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
by: Manning, A, et al.
Published: (2012)

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.
by: Dimas, A, et al.
Published: (2014)

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions
by: Shungin, D, et al.
Published: (2017)

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
by: Scott, R, et al.
Published: (2012)

Coronary calcification with no flow limiting lesions: A potential cause for ischaemic dysfunction in syndrome X patients
by: Elisabetta Palmerini, et al.
Published: (2015-12-01)

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
by: Lagou, V, et al.
Published: (2021)

Lower bounds on the maximum cross correlation of signals /
by: 170524 Welch, L R

Higher education in Southeast Asia : blurring borders, changing balance /
by: Welch, Anthony R.
Published: (2011)

Dektop mapping with personal computer /
by: 272804 Welch, R.

An Approach to the Child with Acute Glomerulonephritis
by: Thomas R. Welch
Published: (2012-01-01)

Ethics in Ethnobiology Publication
by: James R. Welch
Published: (2012-12-01)

A Reply to van der Voort's Response to Welch's Review of "Urihi A: A Terra‐ Floresta Yanomami"
by: James R. Welch
Published: (2011-02-01)

Earth, Wind, and Fire: Pinal Apaches, Miners, and Genocide in Central Arizona, 1859-1874
by: John R. Welch
Published: (2017-12-01)

Engine vibration signals as an aid to fault diagnosis /
by: 233133 Hulls, L. R., et al.
Published: (1967)

Care pathways for people with major depressive disorder
by: R. Strawbridge, et al.
Published: (2022-06-01)

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
by: Wiberg, A, et al.
Published: (2019)

The use of nanoparticles in electroanalysis: a review.
by: Welch, C, et al.
Published: (2006)

Protection in the absence of legislation in Trinidad and Tobago
by: Nakhid, R, et al.
Published: (2017)

Individuality, stability, and variability of the plaque microbiome
by: Daniel R. Utter, et al.
Published: (2016-04-01)

Common lettuce mosaic control: Use of mosaic-free seed effectively reduced the seed-born aphid-transmitted disease in large-scale field plantings
by: R Grogan, et al.
Published: (1952-08-01)

Population structure discovery in meta-analyzed microbial communities and inflammatory bowel disease using MMUPHin
by: Siyuan Ma, et al.
Published: (2022-10-01)

La Loire moyenne naviguée au XIXe siècle : représentations, réglementation et aménagement
by: Yves Lecoeur
Published: (2011-11-01)

Physiological effects of noise/
by: Welch, Bruce L., et al.
Published: (1970)

From words to dates: Water into wine, mathemagic or phylogenetic inference?
by: Atkinson, Q, et al.
Published: (2005)

Mussolini's Greek island : fascism and the Italian occupation of Syros in World War II /
by: 350794 Lecoeur, Sheila
Published: (2009)

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.
by: Barker, A, et al.
Published: (2011)

Sony Labou Tansi : L’Anté-peuple ou le peuple hanté
by: Patrice Yengo
Published: (2015-03-01)

Le ventre dans l’écriture de Sony Labou Tansi et Tchicaya U Tam'si
by: Patrice Yengo
Published: (2014-04-01)

Trois murmures… en un cri
by: Patrice Yengo
Published: (2015-03-01)

L’autre du prophétisme congolais
by: Patrice Yengo
Published: (2019-03-01)

GWAMA: software for genome-wide association meta-analysis
by: Mägi, R, et al.
Published: (2010)

GRANVIL: Rare Variant Analysis of Genome-Wide Association Studies
by: Magi, R, et al.
Published: (2010)

GWAMA: Software Tool for Meta-analysis and Visualization of Whole Genome Association Data
by: Magi, R, et al.
Published: (2009)

Genome-Wide Association Analysis Of Rare Variants With Crohn's Disease
by: Magi, R, et al.
Published: (2012)

Genome-wide association analysis of rare variants identifies potential novel susceptibility genes for type 1 diabetes and coronary artery disease
by: Magi, R, et al.
Published: (2012)

Genome-wide Association Analysis of Rare Variants Identifies Potential Novel Susceptibility Genes for Type 1 Diabetes and Coronary Artery Disease
by: Morris, A, et al.
Published: (2012)

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
by: Morris, A, et al.
Published: (2012)

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
by: Morris, A, et al.
Published: (2012)