DNA damage-induced apoptosis.
Unicellular organisms respond to the presence of DNA lesions by activating cell cycle checkpoint and repair mechanisms, while multicellular animals have acquired the further option of eliminating damaged cells by triggering apoptosis. Defects in DNA damage-induced apoptosis contribute to tumorigenes...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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