Significance of the six peptide-binding pockets of HLA-A2.1 in influenza A matrix peptide-specific cytotoxic T-lymphocyte reactivity.
To evaluate the roles of the six peptide-binding pockets of HLA-A2.1 in FMP-specific CTL recognition, we have constructed an extensive library of HMy2.C1R cell lines expressing mutant HLA-A2.1 molecules with different amino acid substitutions in each of the six pockets. These cell lines were tested...
Päätekijät: | Matsui, M, Moots, R, Mcmichael, A, Frelinger, J |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
1994
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