Cardiomyocyte Na+/H+ exchanger-1 activity is reduced in hypoxia
Fully-activated Na+/H+ exchanger-1 (NHE1) generates the cardiomyocyte’s largest trans-membrane extrusion of H+ ions for an equimolar influx of Na+ ions. This has the desirable effect of clearing excess intracellular acidity, but at a large energetic premium because the exchanged Na+ ions must ultima...
| Hlavní autoři: | , , |
|---|---|
| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
Frontiers Media
2021
|