Cardiomyocyte Na+/H+ exchanger-1 activity is reduced in hypoxia
Fully-activated Na+/H+ exchanger-1 (NHE1) generates the cardiomyocyte’s largest trans-membrane extrusion of H+ ions for an equimolar influx of Na+ ions. This has the desirable effect of clearing excess intracellular acidity, but at a large energetic premium because the exchanged Na+ ions must ultima...
| Hauptverfasser: | , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Frontiers Media
2021
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