Cardiomyocyte Na+/H+ exchanger-1 activity is reduced in hypoxia

Fully-activated Na+/H+ exchanger-1 (NHE1) generates the cardiomyocyte’s largest trans-membrane extrusion of H+ ions for an equimolar influx of Na+ ions. This has the desirable effect of clearing excess intracellular acidity, but at a large energetic premium because the exchanged Na+ ions must ultima...

詳細記述

書誌詳細
主要な著者: Kandilci, H, Richards, M, Swietach, P
フォーマット: Journal article
言語:English
出版事項: Frontiers Media 2021