Human RECQL5 Helicase; A Target Enabling Package

Human RECQL5 Helicase; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. RECQL5 is a member of the RecQ family of helicase which have important functions in DNA repair pathways and maintenance of genome integrity. RECQL5 has recently been identified as a synthetic lethal candidate in various...

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Bibliografiske detaljer
Hovedforfatter:	Gileadi, O
Format:	Dataset
Udgivet:	University of Oxford 2018
Fag:	Structural Genomics Chemical Biology Drug Discovery

Lignende værker

Human RECQL5 Helicase; A Target Enabling Package
af: Newman, J
Udgivet: (2018)

Human RECQL5 Helicase; A Target Enabling Package
af: Newman, J
Udgivet: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
af: Gileadi, O
Udgivet: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Udgivet: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
af: Kopec, J
Udgivet: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
af: Yue, W
Udgivet: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
af: Cox, O
Udgivet: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
af: Cox, O
Udgivet: (2018)

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
af: Dixon-Clarke, S
Udgivet: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Udgivet: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
af: Mathea, S
Udgivet: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
af: Bullock, A
Udgivet: (2018)

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package
Udgivet: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
af: Mathea, S
Udgivet: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
af: Bullock, A
Udgivet: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
af: Pinkas, D
Udgivet: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
af: Pinkas, D
Udgivet: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
af: Brennan, P
Udgivet: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
af: Newman, J
Udgivet: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
af: Newman, J
Udgivet: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
af: Brennan, P
Udgivet: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
af: Brennan, P
Udgivet: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
af: Savitsky, P
Udgivet: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
af: Brennan, P
Udgivet: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
af: Brennan, P
Udgivet: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
af: Savitsky, P
Udgivet: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
af: Carpenter, E
Udgivet: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
af: Chu, A
Udgivet: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
af: Dong, Y
Udgivet: (2018)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
af: Newman, J, et al.
Udgivet: (2017)

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
af: Bassam Abu-Libdeh, et al.
Udgivet: (2022-03-01)

Inhibition of KDM4D and stabilisation of the PHF8 plant homeodomain’s transient structural states using antibodies
af: Wolfreys, F
Udgivet: (2017)

Application of Fragment-Based Drug Discovery to Versatile Targets
af: Qingxin Li
Udgivet: (2020-08-01)

Analysis of multiple compound–protein interactions reveals novel bioactive molecules
af: Hiroaki Yabuuchi, et al.
Udgivet: (2011-03-01)

RECQL5 at the Intersection of Replication and Transcription
af: Zeid Hamadeh, et al.
Udgivet: (2020-05-01)

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer
af: Zhu X, et al.
Udgivet: (2018-12-01)

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.
af: Wilson Castillo-Tandazo, et al.
Udgivet: (2019-07-01)

Connecting genetics and gene expression data for target prioritisation and drug repositioning
af: Enrico Ferrero, et al.
Udgivet: (2018-05-01)

Targeting the ubiquitin system by fragment-based drug discovery
af: Cassandra Kennedy, et al.
Udgivet: (2022-09-01)

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
af: Maria J. Marcaida, et al.
Udgivet: (2020-12-01)